Calcium sulfate artificial bone for repair of thoracolumbar burst fractures

doi:10.3969/j.issn.2095-4344.2014.52.001

Abstract

Abstract:

BACKGROUND: Calcium sulfate artificial bone acts as a kind of bone graft material within the vertebral body, has good fusion effect and can effectively correct sagittal deformity and sequence to maintain the vertebral height.

OBJECTIVE: To assess the clinical effects of calcium sulfate artificial bone in the treatment of thoracolumbar burst fractures.

METHODS: Forty-six thoracolumbar burst fracture patients were randomly divided into a bone graft group

(21 patients undergoing treatment with calcium sulfate artificial bone) and a non-bone graft group (25 patients undergoing vertebroplasty alone). The efficacy of the two types of surgery was compared in terms of postoperative recovery time, visual analog scale score at the final follow-up, anterior vertebral height, incidence of ghost vertebral phenomenon and failure rate of internal fixation.

RESULTS AND CONCLUSION: All patients were followed up for 12 months. Patients in the bone graft group and non-bone graft group were followed up for an average of 18.7 months and 17.48 months, respectively. The postoperative recovery time of patients in the bone graft group was shorter than that in the non-bone graft group (P=0.002); the incidence of ghost vertebral phenomenon and internal fixation failure rate in the bone graft group were lower than those in the non-bone graft group (P=0.036, P=0.038). However, there were no significantly statistical differences between two groups in visual analog scale score at the final follow-up and anterior vertebral height at different time (all P > 0.05). These findings indicate that calcium sulfate artificial bone for thoracolumbar burst fractures is effective and safe, which is superior to vertebroplasty alone.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: calcium sulfate, spinal fractures, vertebroplasty

CLC Number:

R318

Long Hao, Xiao Jie, Zou Wei, Wu Chen, Zhang Yang, Feng Ming-xing, Fu Yong. Calcium sulfate artificial bone for repair of thoracolumbar burst fractures [J]. Chinese Journal of Tissue Engineering Research, 2014, 18(52): 8365-8370.

Figures/Tables 3

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